Generva provides advanced conduits for peripheral nerve regeneration applicable for any damaged peripheral nerve region. Generva also produces nerve protectors that are used for damaged nerve protection and tensionless repair. These products are suturable and it’s easy to fixate the proximal and distal parts into the conduit ends. Their biodegradation rate is in accordance with the nerve reconstruction and it’s possible to design samples according to any customized length and diameter. Generva products are a combination of synthetic and natural biopolymers with nanofibrous structure and homogenous distribution.
Chitin, Chitosan, Glucosamine and Pharmaceutical Salts
crustaceans such as crabs, shrimps, lobsters and some other arthropods contain minerals, organic materials and chitin. Chitin is the primary material for producing chitosan biopolymer. Chitin and Chitosan are produced at industrial scale in some countries of the world. The chemical and biological properties of chitosan have led to its widespread use in many industrial, medical, pharmaceutical, agricultural and food processes The most important applications of this valuable biological material are: wound healing accelerator, stabilizer, concentration and emulsifiers used in the food, pharmaceutical and cosmetics industry, fibers and films, paint coatings, adhesives, papers and fiber reinforcements and etc.
Targeted Drug Delivery System
Amadge formulation is a targeted drug delivery system based on antibodies for controlling and/or treating HER2+ breast cancer in women. This system consists of biopolymer-PEG micelles carrying a chemotherapeutic agent which is conjugated with monoclonal antibody. The product is a monoclonal antibody-based targeted chemotherapeutic delivery with a significant competitive efficacy and lower side effects. The carrier and the preparation method can be applied as a platform to prepare other targeted drug delivery systems using different antibodies or drug pairs for treatment of other cancers such as chronic lymphocytic leukemia cancer or bowel cancer.
Biopolymer Wound Coverings
BIOPATCH produces a wide range of wound coverings (gels, films and patches) made of naturally-derived biopolymers. These chemical-free wound coverings are produced based on specific formulas, physical shapes and applications and then sterilized by gamma-ray irradiation. These US patented products can be used for treating leishmaniasis and various diabetic ulcers and are also available for different cosmetic purposes (removing wrinkles, acnes, surface hydration).
Dara produces advanced hydropolymer wound care dressings fully compatible with the environment and human body. These antibacterial dressings contain nanoparticles of medicinal herbs extracts and vitamin c nanocapsules to boost the performance and maximize the healing process. These products can be used for first and second degree burns, deep pressure ulcers, diabetic ulcers, skin grafts, open fractures wounds, repairing skin damage, hand disinfection and preventing the spread of bacteria.
Bone Regeneration Products
OsteoGen produces bone substitute pieces as replacements for the lost osseous tissue and bone granule and powder as bone void filler or augmentation material for use in periodontal or maxillofacial defects. OsteoGen uses a three dimensional scaffold that mimics the micro-structure, chemical composition and mechanical and functional properties of the native bone tissue to regenerate the damaged bone. With efficient porosity and pore size, this 3D scaffold supports free and optimal cell migration.
Blood Homeostatic Agent
BLOOCKAGE is a uniquely effective hemostatic agent in powder form used for treating arterial hemorrhage and different types of bleeding. This agent is based on dry chitosan powder and can be used for accelerating the blood clotting process in surgeries, dialysis, angiography, angioplasty and treating various injuries. Chitosan is a biodegradable, biocompatible and bioadhesive biopolymer with antibacterial and antifungal properties that can prevent the growth of infection producing bacteria.
Combinational Drug Delivery for Cancer
PAK Therapeutics develops and manufactures cancer multi-drug loaded in hydrophobic and hydrophilic modified biopolymer. This product has the capacity to be used for combinational therapy (for FDA approved drugs) and targeting therapy for cancer treatment. Based on therapy, the anticancer drug market is segmented into immunotherapy, targeted therapy and chemotherapy. The segment for targeted drugs accounts for more than 40% of share value in the global drugs market for anti-cancer. As compared to cytotoxic drugs, targeted therapy has minimum side effects along with effective results and high specificity.
Immune System Booster Supplements
IMMUNABLE is an immune system supplement; a modern product based on the indigenous knowledge of Persian traditional medicine heritage that is proven to be effective. With its 100% herbal formulation, this supplement helps to strengthen the immune system against various diseases, especially cancer.